What is a common cause of resistance in HIV treatment?

Non-adherence to the prescribed regimen is a well-documented and significant cause of resistance in HIV treatment. When patients do not take their antiretroviral medications as directed—whether due to forgetfulness, misunderstandings about the importance of the regimen, or side effects—the level of the virus in their body can rise. Incomplete dosing allows the virus to replicate and mutate, potentially leading to the development of resistance against the medications being used. This resistance can make future treatment options less effective or even ineffective, complicating the patient's management. Therefore, adherence to the treatment regimen is crucial for maintaining viral suppression and preventing resistance.